siRNA, Anti-LGMN, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT16640WQ-2OMe)

The product SIRGT16640WQ-2OMe is a type of small interfering RNA (siRNA) that targets LGMN gene and regulates the expression of gene. The siRNA interferes with the expression of LGMN gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001008530.2; NM_005606.6
Alternative Names AEP; LGMN1; PRSC1
Related Diseases Corneal Dystrophy, Subepithelial Mucinous
Purification HPLC
Target Gene
Gene ID 5641
Uniprot ID Q99538
Sub Cat Target Species Modification Scale  
SIRGT17640WQ-2F LGMN Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18640WQ-2MOE LGMN Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT16640WQ-RB LGMN Human Ribo-modified Inquiry
SIRGT17640WQ-BB LGMN Human Backbone-modified Inquiry

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