siRNA, Anti-LHX1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11576WQ-2OMe)

The product SIRGT11576WQ-2OMe is a type of small interfering RNA (siRNA) that targets LHX1 gene and regulates the expression of gene. The siRNA interferes with the expression of LHX1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005568.4
Alternative Names LIM-1; LIM1
Related Diseases Mayer-Rokitansky-Kuster-Hauser Syndrome
Purification HPLC
Target Gene
Gene ID 3975
Uniprot ID P48742
Sub Cat Target Species Modification Scale  
SIRGT12576WQ-2F LHX1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13576WQ-2MOE LHX1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14576WQ-LNA LHX1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11576WQ-RB LHX1 Human Ribo-modified Inquiry
SIRGT12576WQ-BB LHX1 Human Backbone-modified Inquiry

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