siRNA, Anti-LONRF3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46248WQ-2OMe)

The product SIRGT46248WQ-2OMe is a type of small interfering RNA (siRNA) that targets LONRF3 gene and regulates the expression of gene. The siRNA interferes with the expression of LONRF3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001031855.2
Alternative Names RNF127
Related Diseases Ankyloglossia With Or Without Tooth Anomalies
Purification HPLC
Target Gene
Gene ID 79836
Uniprot ID Q496Y0
Sub Cat Target Species Modification Scale  
SIRGT47248WQ-2F LONRF3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48248WQ-2MOE LONRF3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49248WQ-LNA LONRF3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46248WQ-RB LONRF3 Human Ribo-modified Inquiry
SIRGT47248WQ-BB LONRF3 Human Backbone-modified Inquiry

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