siRNA, Anti-LOXL1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11606WQ-2OMe)

The product SIRGT11606WQ-2OMe is a type of small interfering RNA (siRNA) that targets LOXL1 gene and regulates the expression of gene. The siRNA interferes with the expression of LOXL1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005576.3
Alternative Names LOL; LOXL
Related Diseases Exfoliation syndrome
Purification HPLC
Target Gene
Gene ID 4016
Uniprot ID Q08397
Sub Cat Target Species Modification Scale  
SIRGT12606WQ-2F LOXL1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13606WQ-2MOE LOXL1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14606WQ-LNA LOXL1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11606WQ-RB LOXL1 Human Ribo-modified Inquiry
SIRGT12606WQ-BB LOXL1 Human Backbone-modified Inquiry

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