siRNA, Anti-LPA, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11608WQ-2OMe)

The product SIRGT11608WQ-2OMe is a type of small interfering RNA (siRNA) that targets LPA gene and regulates the expression of gene. The siRNA interferes with the expression of LPA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005577.2
Alternative Names AK38; APOA; LP
Related Diseases Peripheral Vascular Disease
Purification HPLC
Target Gene
Gene ID 4018
Uniprot ID P08519
Sub Cat Target Species Modification Scale  
SIRGT12608WQ-2F LPA Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13608WQ-2MOE LPA Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14608WQ-LNA LPA Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11608WQ-RB LPA Human Ribo-modified Inquiry
SIRGT12608WQ-BB LPA Human Backbone-modified Inquiry

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