siRNA, Anti-LUM, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11635WQ-2OMe)

The product SIRGT11635WQ-2OMe is a type of small interfering RNA (siRNA) that targets LUM gene and regulates the expression of gene. The siRNA interferes with the expression of LUM gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002345.3
Alternative Names LDC; SLRR2D
Related Diseases Cornea Plana, Corneal Dystrophy
Purification HPLC
Target Gene
Gene ID 4060
Uniprot ID P51884
Sub Cat Target Species Modification Scale  
SIRGT12635WQ-2F LUM Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13635WQ-2MOE LUM Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14635WQ-LNA LUM Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11635WQ-RB LUM Human Ribo-modified Inquiry
SIRGT12635WQ-BB LUM Human Backbone-modified Inquiry

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