siRNA, Anti-LYST, 2'-F/2'-OMe/2'-MOE/Backbone-modified(CAT#: SIRGT01780WQ-2OMe)

The product SIRGT01780WQ-2OMe is a type of small interfering RNA (siRNA) that targets LYST gene and regulates the expression of gene. The siRNA interferes with the expression of LYST gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000081.3; NM_001301365.1
Alternative Names CHS; CHS1
Related Diseases Chediak-Higashi Syndrome
Purification HPLC
Target Gene
Gene ID 1130
Uniprot ID Q99698
Sub Cat Target Species Modification Scale  
SIRGT02780WQ-2F LYST Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03780WQ-2MOE LYST Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT02780WQ-BB LYST Human Backbone-modified Inquiry

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