siRNA, Anti-MAGEL2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41222WQ-2OMe)

The product SIRGT41222WQ-2OMe is a type of small interfering RNA (siRNA) that targets MAGEL2 gene and regulates the expression of gene. The siRNA interferes with the expression of MAGEL2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_019066.4
Alternative Names NDNL1; PWLS; SHFYNG; nM15
Related Diseases Schaaf-Yang Syndrome
Purification HPLC
Target Gene
Gene ID 54551
Uniprot ID Q9UJ55
Sub Cat Target Species Modification Scale  
SIRGT42222WQ-2F MAGEL2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43222WQ-2MOE MAGEL2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44222WQ-LNA MAGEL2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41222WQ-RB MAGEL2 Human Ribo-modified Inquiry
SIRGT42222WQ-BB MAGEL2 Human Backbone-modified Inquiry

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