siRNA, Anti-MAP1B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11687WQ-2OMe)

The product SIRGT11687WQ-2OMe is a type of small interfering RNA (siRNA) that targets MAP1B gene and regulates the expression of gene. The siRNA interferes with the expression of MAP1B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001324255.1; NM_005909.4
Alternative Names FUTSCH; MAP5; PPP1R102
Related Diseases Periventricular Nodular Heterotopia
Purification HPLC
Target Gene
Gene ID 4131
Uniprot ID P46821
Sub Cat Target Species Modification Scale  
SIRGT12687WQ-2F MAP1B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13687WQ-2MOE MAP1B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14687WQ-LNA MAP1B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11687WQ-RB MAP1B Human Ribo-modified Inquiry
SIRGT12687WQ-BB MAP1B Human Backbone-modified Inquiry

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