siRNA, Anti-MAP2K1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo-modified(CAT#: SIRGT16612WQ-2OMe)

The product SIRGT16612WQ-2OMe is a type of small interfering RNA (siRNA) that targets MAP2K1 gene and regulates the expression of gene. The siRNA interferes with the expression of MAP2K1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002755.3
Alternative Names CFC3; MAPKK1; MEK1; MKK1; PRKMK1
Related Diseases Cardiofaciocutaneous Syndrome
Purification HPLC
Target Gene
Gene ID 5604
Uniprot ID Q02750
Sub Cat Target Species Modification Scale  
SIRGT17612WQ-2F MAP2K1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18612WQ-2MOE MAP2K1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19612WQ-LNA MAP2K1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16612WQ-RB MAP2K1 Human Ribo-modified Inquiry

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