siRNA, Anti-MAP2K5, 2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16615WQ-2OMe)

The product SIRGT16615WQ-2OMe is a type of small interfering RNA (siRNA) that targets MAP2K5 gene and regulates the expression of gene. The siRNA interferes with the expression of MAP2K5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001206804.1; NM_002757.3; NM_145160.2
Alternative Names HsT17454; MAPKK5; MEK5; PRKMK5
Related Diseases Restless Legs Syndrome
Purification HPLC
Target Gene
Gene ID 5607
Uniprot ID Q13163
Sub Cat Target Species Modification Scale  
SIRGT18615WQ-2MOE MAP2K5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19615WQ-LNA MAP2K5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16615WQ-RB MAP2K5 Human Ribo-modified Inquiry
SIRGT17615WQ-BB MAP2K5 Human Backbone-modified Inquiry

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