siRNA, Anti-MAP3K3, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT11745WQ-2OMe)

The product SIRGT11745WQ-2OMe is a type of small interfering RNA (siRNA) that targets MAP3K3 gene and regulates the expression of gene. The siRNA interferes with the expression of MAP3K3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001330431.1; NM_002401.3; NM_203351.1
Alternative Names MAPKKK3; MEKK3
Related Diseases Cerebral Cavernous Malformations
Purification HPLC
Target Gene
Gene ID 4215
Uniprot ID Q99759
Sub Cat Target Species Modification Scale  
SIRGT12745WQ-2F MAP3K3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT14745WQ-LNA MAP3K3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11745WQ-RB MAP3K3 Human Ribo-modified Inquiry
SIRGT12745WQ-BB MAP3K3 Human Backbone-modified Inquiry

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