siRNA, Anti-MARCHF1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41472WQ-2OMe)

The product SIRGT41472WQ-2OMe is a type of small interfering RNA (siRNA) that targets MARCHF1 gene and regulates the expression of gene. The siRNA interferes with the expression of MARCHF1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001166373.1
Alternative Names MARCH-I; RNF171; MARCH1
Related Diseases Febrile Seizures, Familial, 11
Purification HPLC
Target Gene
Gene ID 55016
Uniprot ID Q8TCQ1
Sub Cat Target Species Modification Scale  
SIRGT42472WQ-2F MARCHF1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43472WQ-2MOE MARCHF1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44472WQ-LNA MARCHF1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41472WQ-RB MARCHF1 Human Ribo-modified Inquiry
SIRGT42472WQ-BB MARCHF1 Human Backbone-modified Inquiry

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