siRNA, Anti-MARCKS, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11651WQ-2OMe)

The product SIRGT11651WQ-2OMe is a type of small interfering RNA (siRNA) that targets MARCKS gene and regulates the expression of gene. The siRNA interferes with the expression of MARCKS gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002356.6
Alternative Names 80K-L; MACS; PKCSL; PRKCSL
Related Diseases Spinocerebellar Ataxia 14, Anencephaly
Purification HPLC
Target Gene
Gene ID 4082
Uniprot ID P29966
Sub Cat Target Species Modification Scale  
SIRGT12651WQ-2F MARCKS Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13651WQ-2MOE MARCKS Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14651WQ-LNA MARCKS Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11651WQ-RB MARCKS Human Ribo-modified Inquiry
SIRGT12651WQ-BB MARCKS Human Backbone-modified Inquiry

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