siRNA, Anti-MATN3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11700WQ-2OMe)

The product SIRGT11700WQ-2OMe is a type of small interfering RNA (siRNA) that targets MATN3 gene and regulates the expression of gene. The siRNA interferes with the expression of MATN3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002381.4
Alternative Names DIPOA; EDM5; HOA; OADIP; OS2
Related Diseases Spondyloepimetaphyseal Dysplasia
Purification HPLC
Target Gene
Gene ID 4148
Uniprot ID O15232
Sub Cat Target Species Modification Scale  
SIRGT12700WQ-2F MATN3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13700WQ-2MOE MATN3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14700WQ-LNA MATN3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11700WQ-RB MATN3 Human Ribo-modified Inquiry
SIRGT12700WQ-BB MATN3 Human Backbone-modified Inquiry

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