siRNA, Anti-MEIS1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11742WQ-2OMe)

The product SIRGT11742WQ-2OMe is a type of small interfering RNA (siRNA) that targets MEIS1 gene and regulates the expression of gene. The siRNA interferes with the expression of MEIS1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002398.2
Related Diseases Restless Legs Syndrome
Purification HPLC
Target Gene
Gene ID 4211
Uniprot ID O00470
Sub Cat Target Species Modification Scale  
SIRGT12742WQ-2F MEIS1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13742WQ-2MOE MEIS1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14742WQ-LNA MEIS1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11742WQ-RB MEIS1 Human Ribo-modified Inquiry
SIRGT12742WQ-BB MEIS1 Human Backbone-modified Inquiry

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