siRNA, Anti-MGEA5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT36028WQ-2OMe)

The product SIRGT36028WQ-2OMe is a type of small interfering RNA (siRNA) that targets MGEA5 gene and regulates the expression of gene. The siRNA interferes with the expression of MGEA5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001142434.1; NM_012215.3
Alternative Names MEA5; NCOAT; OGA
Related Diseases Gm2 Gangliosidosis
Purification HPLC
Target Gene
Gene ID 10724
Uniprot ID O60502
Sub Cat Target Species Modification Scale  
SIRGT37028WQ-2F MGEA5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT38028WQ-2MOE MGEA5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT39028WQ-LNA MGEA5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36028WQ-RB MGEA5 Human Ribo-modified Inquiry
SIRGT37028WQ-BB MGEA5 Human Backbone-modified Inquiry

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