siRNA, Anti-MGRN1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT36844WQ-2OMe)

The product SIRGT36844WQ-2OMe is a type of small interfering RNA (siRNA) that targets MGRN1 gene and regulates the expression of gene. The siRNA interferes with the expression of MGRN1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001142289.2
Alternative Names RNF156
Related Diseases Amyotrophic Lateral Sclerosis
Purification HPLC
Target Gene
Gene ID 23295
Uniprot ID O60291
Sub Cat Target Species Modification Scale  
SIRGT37844WQ-2F MGRN1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT38844WQ-2MOE MGRN1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT39844WQ-LNA MGRN1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36844WQ-RB MGRN1 Human Ribo-modified Inquiry
SIRGT37844WQ-BB MGRN1 Human Backbone-modified Inquiry

Related Products