siRNA, Anti-MKLN1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11786WQ-2OMe)

The product SIRGT11786WQ-2OMe is a type of small interfering RNA (siRNA) that targets MKLN1 gene and regulates the expression of gene. The siRNA interferes with the expression of MKLN1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001145354.1; NM_001321316.1; NM_013255.4
Alternative Names TWA2
Related Diseases Lissencephaly
Purification HPLC
Target Gene
Gene ID 4289
Uniprot ID Q9UL63
Sub Cat Target Species Modification Scale  
SIRGT12786WQ-2F MKLN1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13786WQ-2MOE MKLN1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14786WQ-LNA MKLN1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11786WQ-RB MKLN1 Human Ribo-modified Inquiry
SIRGT12786WQ-BB MKLN1 Human Backbone-modified Inquiry

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