siRNA, Anti-MKS1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41375WQ-2OMe)

The product SIRGT41375WQ-2OMe is a type of small interfering RNA (siRNA) that targets MKS1 gene and regulates the expression of gene. The siRNA interferes with the expression of MKS1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001165927.1
Alternative Names BBS13; JBTS28; MES; MKS; POC12
Related Diseases Meckel Syndrome, Type 1
Purification HPLC
Target Gene
Gene ID 54903
Uniprot ID Q9NXB0
Sub Cat Target Species Modification Scale  
SIRGT42375WQ-2F MKS1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43375WQ-2MOE MKS1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44375WQ-LNA MKS1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41375WQ-RB MKS1 Human Ribo-modified Inquiry
SIRGT42375WQ-BB MKS1 Human Backbone-modified Inquiry

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