siRNA, Anti-MLANA, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06564WQ-2OMe)

The product SIRGT06564WQ-2OMe is a type of small interfering RNA (siRNA) that targets MLANA gene and regulates the expression of gene. The siRNA interferes with the expression of MLANA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005511.1
Alternative Names MART-1; MART1
Related Diseases Angiomyolipoma, Perivascular Epithelioid Cell Tumor
Purification HPLC
Target Gene
Gene ID 2315
Uniprot ID Q16655
Sub Cat Target Species Modification Scale  
SIRGT07564WQ-2F MLANA Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08564WQ-2MOE MLANA Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09564WQ-LNA MLANA Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06564WQ-RB MLANA Human Ribo-modified Inquiry
SIRGT07564WQ-BB MLANA Human Backbone-modified Inquiry

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