siRNA, Anti-MTCL1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT36815WQ-2OMe)

The product SIRGT36815WQ-2OMe is a type of small interfering RNA (siRNA) that targets MTCL1 gene and regulates the expression of gene. The siRNA interferes with the expression of MTCL1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_015210.3
Alternative Names CCDC165; KIAA0802; SOGA2
Related Diseases Niemann-Pick Disease, Type C1
Purification HPLC
Target Gene
Gene ID 23255
Uniprot ID Q9Y4B5
Sub Cat Target Species Modification Scale  
SIRGT37815WQ-2F MTCL1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT38815WQ-2MOE MTCL1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT39815WQ-LNA MTCL1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36815WQ-RB MTCL1 Human Ribo-modified Inquiry
SIRGT37815WQ-BB MTCL1 Human Backbone-modified Inquiry

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