siRNA, Anti-MTHFR, LNA-modified(CAT#: SIRGT14870WQ-LNA)

The product SIRGT14870WQ-LNA is a type of small interfering RNA (siRNA) that targets MTHFR gene and regulates the expression of gene. The siRNA interferes with the expression of MTHFR gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_001330358.1; NM_005957.4
Related Diseases Neural Tube Defects, Folate-Sensitive
Purification HPLC
Target Gene
Gene ID 4524
Uniprot ID P42898

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