siRNA, Anti-MTNR1A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo-modified(CAT#: SIRGT11874WQ-2OMe)

The product SIRGT11874WQ-2OMe is a type of small interfering RNA (siRNA) that targets MTNR1A gene and regulates the expression of gene. The siRNA interferes with the expression of MTNR1A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005958.4
Alternative Names MEL-1A-R; MT1
Related Diseases Periodic Limb Movement Disorder
Purification HPLC
Target Gene
Gene ID 4543
Uniprot ID P48039
Sub Cat Target Species Modification Scale  
SIRGT12874WQ-2F MTNR1A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13874WQ-2MOE MTNR1A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14874WQ-LNA MTNR1A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11874WQ-RB MTNR1A Human Ribo-modified Inquiry

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