siRNA, Anti-MXD4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31946WQ-2OMe)

The product SIRGT31946WQ-2OMe is a type of small interfering RNA (siRNA) that targets MXD4 gene and regulates the expression of gene. The siRNA interferes with the expression of MXD4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_006454.2
Alternative Names MAD4; MST149; MSTP149; bHLHc12
Related Diseases Extracranial Neuroblastoma, Adrenal Neuroblastoma
Purification HPLC
Target Gene
Gene ID 10608
Uniprot ID Q14582
Sub Cat Target Species Modification Scale  
SIRGT32946WQ-2F MXD4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33946WQ-2MOE MXD4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34946WQ-LNA MXD4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31946WQ-RB MXD4 Human Ribo-modified Inquiry
SIRGT32946WQ-BB MXD4 Human Backbone-modified Inquiry

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