siRNA, Anti-NANOG, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46315WQ-2OMe)

The product SIRGT46315WQ-2OMe is a type of small interfering RNA (siRNA) that targets NANOG gene and regulates the expression of gene. The siRNA interferes with the expression of NANOG gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001297698.1
Related Diseases Teratocarcinoma
Purification HPLC
Target Gene
Gene ID 79923
Uniprot ID Q9H9S0
Sub Cat Target Species Modification Scale  
SIRGT47315WQ-2F NANOG Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48315WQ-2MOE NANOG Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49315WQ-LNA NANOG Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46315WQ-RB NANOG Human Ribo-modified Inquiry
SIRGT47315WQ-BB NANOG Human Backbone-modified Inquiry

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