siRNA, Anti-NCK1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT11960WQ-2OMe)

The product SIRGT11960WQ-2OMe is a type of small interfering RNA (siRNA) that targets NCK1 gene and regulates the expression of gene. The siRNA interferes with the expression of NCK1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001190796.2; NM_001291999.1; NM_006153.5
Alternative Names NCK; NCKalpha; nck-1
Related Diseases Wiskott-Aldrich Syndrome, Vaccinia
Purification HPLC
Target Gene
Gene ID 4690
Uniprot ID P16333
Sub Cat Target Species Modification Scale  
SIRGT12960WQ-2F NCK1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13960WQ-2MOE NCK1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT11960WQ-RB NCK1 Human Ribo-modified Inquiry
SIRGT12960WQ-BB NCK1 Human Backbone-modified Inquiry

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