siRNA, Anti-NCS1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT36937WQ-2OMe)

The product SIRGT36937WQ-2OMe is a type of small interfering RNA (siRNA) that targets NCS1 gene and regulates the expression of gene. The siRNA interferes with the expression of NCS1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001128826.1
Alternative Names FLUP; FREQ
Related Diseases Wolfram Syndrome
Purification HPLC
Target Gene
Gene ID 23413
Uniprot ID P62166
Sub Cat Target Species Modification Scale  
SIRGT37937WQ-2F NCS1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT38937WQ-2MOE NCS1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT36937WQ-RB NCS1 Human Ribo-modified Inquiry
SIRGT37937WQ-BB NCS1 Human Backbone-modified Inquiry

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