siRNA, Anti-NDC1, 2'-F/2'-OMe/2'-MOE/LNA/Backbone-modified(CAT#: SIRGT41849WQ-2OMe)

The product SIRGT41849WQ-2OMe is a type of small interfering RNA (siRNA) that targets NDC1 gene and regulates the expression of gene. The siRNA interferes with the expression of NDC1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001168551.1
Alternative Names NET3; TMEM48
Related Diseases Achalasia-Addisonianism-Alacrima Syndrome
Purification HPLC
Target Gene
Gene ID 55706
Uniprot ID Q9BTX1
Sub Cat Target Species Modification Scale  
SIRGT42849WQ-2F NDC1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43849WQ-2MOE NDC1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44849WQ-LNA NDC1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT42849WQ-BB NDC1 Human Backbone-modified Inquiry

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