siRNA, Anti-NDUFA2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11965WQ-2OMe)

The product SIRGT11965WQ-2OMe is a type of small interfering RNA (siRNA) that targets NDUFA2 gene and regulates the expression of gene. The siRNA interferes with the expression of NDUFA2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001185012.1; NM_002488.4
Alternative Names B8; CD14; CIB8
Related Diseases Leigh syndrome
Purification HPLC
Target Gene
Gene ID 4695
Uniprot ID O43678
Sub Cat Target Species Modification Scale  
SIRGT12965WQ-2F NDUFA2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13965WQ-2MOE NDUFA2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14965WQ-LNA NDUFA2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11965WQ-RB NDUFA2 Human Ribo-modified Inquiry
SIRGT12965WQ-BB NDUFA2 Human Backbone-modified Inquiry

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