siRNA, Anti-NDUFA6, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11969WQ-2OMe)

The product SIRGT11969WQ-2OMe is a type of small interfering RNA (siRNA) that targets NDUFA6 gene and regulates the expression of gene. The siRNA interferes with the expression of NDUFA6 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002490.4
Alternative Names B14; CI-B14; LYRM6; NADHB14
Related Diseases Mitochondrial Disorders
Purification HPLC
Target Gene
Gene ID 4700
Uniprot ID P56556
Sub Cat Target Species Modification Scale  
SIRGT12969WQ-2F NDUFA6 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13969WQ-2MOE NDUFA6 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14969WQ-LNA NDUFA6 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11969WQ-RB NDUFA6 Human Ribo-modified Inquiry
SIRGT12969WQ-BB NDUFA6 Human Backbone-modified Inquiry

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