siRNA, Anti-NDUFB5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo-modified(CAT#: SIRGT11980WQ-2OMe)

The product SIRGT11980WQ-2OMe is a type of small interfering RNA (siRNA) that targets NDUFB5 gene and regulates the expression of gene. The siRNA interferes with the expression of NDUFB5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001199957.1; NM_001199958.1; NM_002492.3
Alternative Names CISGDH; SGDH
Related Diseases Pseudobulbar Palsy, Night Blindness
Purification HPLC
Target Gene
Gene ID 4711
Uniprot ID O43674
Sub Cat Target Species Modification Scale  
SIRGT12980WQ-2F NDUFB5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13980WQ-2MOE NDUFB5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14980WQ-LNA NDUFB5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11980WQ-RB NDUFB5 Human Ribo-modified Inquiry

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