siRNA, Anti-NHEJ1, 2'-OMe-modified(CAT#: SIRGT46252WQ-2OMe)

The product SIRGT46252WQ-2OMe is a type of small interfering RNA (siRNA) that targets NHEJ1 gene and regulates the expression of gene. The siRNA interferes with the expression of NHEJ1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification 2ʹ-O-methyl (2'-OMe)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_024782.2
Alternative Names XLF
Related Diseases Severe Combined Immunodeficiency
Purification HPLC
Target Gene
Gene ID 79840
Uniprot ID Q9H9Q4

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