siRNA, Anti-NICN1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46875WQ-2OMe)

The product SIRGT46875WQ-2OMe is a type of small interfering RNA (siRNA) that targets NICN1 gene and regulates the expression of gene. The siRNA interferes with the expression of NICN1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_032316.3
Related Diseases Glycine Encephalopathy
Purification HPLC
Target Gene
Gene ID 84276
Uniprot ID Q9BSH3
Sub Cat Target Species Modification Scale  
SIRGT47875WQ-2F NICN1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48875WQ-2MOE NICN1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49875WQ-LNA NICN1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46875WQ-RB NICN1 Human Ribo-modified Inquiry
SIRGT47875WQ-BB NICN1 Human Backbone-modified Inquiry

Related Products