siRNA, Anti-NKX1-1, 2'-OMe/LNA/Backbone-modified(CAT#: SIRGT41251WQ-2OMe)
The product SIRGT41251WQ-2OMe is a type of small interfering RNA (siRNA) that targets NKX1-1 gene and regulates the expression of gene. The siRNA interferes with the expression of NKX1-1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001290079.1 |
| Alternative Names | HSPX153; NKX-1.1; SAX2 |
| Related Diseases | Orofaciodigital Syndrome Viii |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT44251WQ-LNA | NKX1-1 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT42251WQ-BB | NKX1-1 | Human | Backbone-modified |
