siRNA, Anti-NKX3-2, 2'-F/LNA-modified(CAT#: SIRGT02381WQ-2F)
The product SIRGT02381WQ-2F is a type of small interfering RNA (siRNA) that targets NKX3-2 gene and regulates the expression of gene. The siRNA interferes with the expression of NKX3-2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001189.3 |
| Alternative Names | BAPX1; NKX3.2; NKX3B; SMMD |
| Related Diseases | Spondylo-Megaepiphyseal-Metaphyseal Dysplasia, Bone Osteosarcoma |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT04381WQ-LNA | NKX3-2 | Human | Locked Nucleic Acid (LNA) |
