siRNA, Anti-NLRC5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46807WQ-2OMe)

The product SIRGT46807WQ-2OMe is a type of small interfering RNA (siRNA) that targets NLRC5 gene and regulates the expression of gene. The siRNA interferes with the expression of NLRC5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001330552.1
Alternative Names CLR16.1; NOD27; NOD4
Related Diseases Familial Pityriasis Rubra Pilaris
Purification HPLC
Target Gene
Gene ID 84166
Uniprot ID Q86WI3
Sub Cat Target Species Modification Scale  
SIRGT47807WQ-2F NLRC5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48807WQ-2MOE NLRC5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49807WQ-LNA NLRC5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46807WQ-RB NLRC5 Human Ribo-modified Inquiry
SIRGT47807WQ-BB NLRC5 Human Backbone-modified Inquiry

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