siRNA, Anti-NOA1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46872WQ-2OMe)

The product SIRGT46872WQ-2OMe is a type of small interfering RNA (siRNA) that targets NOA1 gene and regulates the expression of gene. The siRNA interferes with the expression of NOA1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_032313.3
Alternative Names C4orf14; MTG3; hAtNOS1; hNOA1; mAtNOS1
Related Diseases Spinocerebellar Ataxia
Purification HPLC
Target Gene
Gene ID 84273
Uniprot ID Q8NC60
Sub Cat Target Species Modification Scale  
SIRGT47872WQ-2F NOA1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48872WQ-2MOE NOA1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49872WQ-LNA NOA1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46872WQ-RB NOA1 Human Ribo-modified Inquiry
SIRGT47872WQ-BB NOA1 Human Backbone-modified Inquiry

Related Products