siRNA, Anti-NOLC1, 2'-F/2'-OMe/2'-MOE/LNA-modified(CAT#: SIRGT26870WQ-2OMe)

The product SIRGT26870WQ-2OMe is a type of small interfering RNA (siRNA) that targets NOLC1 gene and regulates the expression of gene. The siRNA interferes with the expression of NOLC1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001284388.1; NM_001284389.1; NM_004741.4
Alternative Names NOPP130; NOPP140; NS5ATP13; P130
Related Diseases Treacher Collins Syndrome
Purification HPLC
Target Gene
Gene ID 9221
Uniprot ID Q14978
Sub Cat Target Species Modification Scale  
SIRGT27870WQ-2F NOLC1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28870WQ-2MOE NOLC1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29870WQ-LNA NOLC1 Human Locked Nucleic Acid (LNA) Inquiry

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