siRNA, Anti-NOTCH4, 2'-F-modified(CAT#: SIRGT17079WQ-2F)

The product SIRGT17079WQ-2F is a type of small interfering RNA (siRNA) that targets NOTCH4 gene and regulates the expression of gene. The siRNA interferes with the expression of NOTCH4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification 2ʹ-deoxy-2ʹ-fluoro (2'-F)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_004557.3
Alternative Names INT3
Related Diseases Arteriovenous Malformation, Schizoaffective Disorder
Purification HPLC
Target Gene
Gene ID 4855
Uniprot ID Q99466

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