siRNA, Anti-NR0B1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT01127WQ-2OMe)

The product SIRGT01127WQ-2OMe is a type of small interfering RNA (siRNA) that targets NR0B1 gene and regulates the expression of gene. The siRNA interferes with the expression of NR0B1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000475.4
Alternative Names AHC; AHCH; AHX; DAX-1; DAX1; DSS; GTD; HHG; NROB1; SRXY2
Related Diseases Adrenal Hypoplasia
Purification HPLC
Target Gene
Gene ID 190
Uniprot ID P51843
Sub Cat Target Species Modification Scale  
SIRGT02127WQ-2F NR0B1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03127WQ-2MOE NR0B1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT01127WQ-RB NR0B1 Human Ribo-modified Inquiry
SIRGT02127WQ-BB NR0B1 Human Backbone-modified Inquiry

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