siRNA, Anti-NRXN2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26972WQ-2OMe)

The product SIRGT26972WQ-2OMe is a type of small interfering RNA (siRNA) that targets NRXN2 gene and regulates the expression of gene. The siRNA interferes with the expression of NRXN2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_015080.3; NM_138732.2; NM_138734.2
Related Diseases Childhood Disintegrative Disease
Purification HPLC
Target Gene
Gene ID 9379
Uniprot ID P58401
Sub Cat Target Species Modification Scale  
SIRGT27972WQ-2F NRXN2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28972WQ-2MOE NRXN2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29972WQ-LNA NRXN2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26972WQ-RB NRXN2 Human Ribo-modified Inquiry
SIRGT27972WQ-BB NRXN2 Human Backbone-modified Inquiry

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