siRNA, Anti-NSMCE4A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41277WQ-2OMe)

The product SIRGT41277WQ-2OMe is a type of small interfering RNA (siRNA) that targets NSMCE4A gene and regulates the expression of gene. The siRNA interferes with the expression of NSMCE4A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001167865.1
Alternative Names C10orf86; NS4EA; NSE4A
Related Diseases Amyotrophic Lateral Sclerosis
Purification HPLC
Target Gene
Gene ID 54780
Uniprot ID Q9NXX6
Sub Cat Target Species Modification Scale  
SIRGT42277WQ-2F NSMCE4A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43277WQ-2MOE NSMCE4A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44277WQ-LNA NSMCE4A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41277WQ-RB NSMCE4A Human Ribo-modified Inquiry
SIRGT42277WQ-BB NSMCE4A Human Backbone-modified Inquiry

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