siRNA, Anti-NVL, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT16132WQ-2OMe)

The product SIRGT16132WQ-2OMe is a type of small interfering RNA (siRNA) that targets NVL gene and regulates the expression of gene. The siRNA interferes with the expression of NVL gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001243146.1; NM_001243147.1; NM_002533.3; NM_206840.2
Alternative Names NVL2
Related Diseases Chromosome 1Q41-Q42 Deletion Syndrome.
Purification HPLC
Target Gene
Gene ID 4931
Uniprot ID O15381
Sub Cat Target Species Modification Scale  
SIRGT17132WQ-2F NVL Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT19132WQ-LNA NVL Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16132WQ-RB NVL Human Ribo-modified Inquiry
SIRGT17132WQ-BB NVL Human Backbone-modified Inquiry

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