siRNA, Anti-PCCB, 2'-F/LNA/Ribo/Backbone-modified(CAT#: SIRGT17236WQ-2F)
The product SIRGT17236WQ-2F is a type of small interfering RNA (siRNA) that targets PCCB gene and regulates the expression of gene. The siRNA interferes with the expression of PCCB gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_000532.4; NM_001178014.1 |
| Related Diseases | Propionic Acidemia, Biotinidase Deficiency |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT19236WQ-LNA | PCCB | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT16236WQ-RB | PCCB | Human | Ribo-modified | ||
| SIRGT17236WQ-BB | PCCB | Human | Backbone-modified |
