siRNA, Anti-PDE3A, LNA-modified(CAT#: SIRGT19265WQ-LNA)

The product SIRGT19265WQ-LNA is a type of small interfering RNA (siRNA) that targets PDE3A gene and regulates the expression of gene. The siRNA interferes with the expression of PDE3A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_000921.4; NM_001244683.1
Alternative Names CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB
Related Diseases Hypertension And Brachydactyly Syndrome
Purification HPLC
Target Gene
Gene ID 5139
Uniprot ID Q14432

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