siRNA, Anti-PDGFA, 2'-F/2'-OMe/2'-MOE/Ribo-modified(CAT#: SIRGT16280WQ-2OMe)

The product SIRGT16280WQ-2OMe is a type of small interfering RNA (siRNA) that targets PDGFA gene and regulates the expression of gene. The siRNA interferes with the expression of PDGFA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002607.5; NM_033023.4
Alternative Names PDGF-A; PDGF1
Related Diseases Denys-Drash Syndrome
Purification HPLC
Target Gene
Gene ID 5154
Uniprot ID P04085
Sub Cat Target Species Modification Scale  
SIRGT17280WQ-2F PDGFA Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18280WQ-2MOE PDGFA Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT16280WQ-RB PDGFA Human Ribo-modified Inquiry

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