siRNA, Anti-PER1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16305WQ-2OMe)

The product SIRGT16305WQ-2OMe is a type of small interfering RNA (siRNA) that targets PER1 gene and regulates the expression of gene. The siRNA interferes with the expression of PER1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002616.2
Alternative Names PER; RIGUI; hPER
Related Diseases Advanced Sleep Phase Syndrome
Purification HPLC
Target Gene
Gene ID 5187
Uniprot ID O15534
Sub Cat Target Species Modification Scale  
SIRGT17305WQ-2F PER1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18305WQ-2MOE PER1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19305WQ-LNA PER1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16305WQ-RB PER1 Human Ribo-modified Inquiry
SIRGT17305WQ-BB PER1 Human Backbone-modified Inquiry

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