siRNA, Anti-PFKFB1, 2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT16323WQ-2OMe)

The product SIRGT16323WQ-2OMe is a type of small interfering RNA (siRNA) that targets PFKFB1 gene and regulates the expression of gene. The siRNA interferes with the expression of PFKFB1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001271804.1; NM_001271805.1; NM_002625.3
Alternative Names F6PK; HL2K; PFRX
Related Diseases Hepatocellular Carcinoma
Purification HPLC
Target Gene
Gene ID 5207
Uniprot ID P16118
Sub Cat Target Species Modification Scale  
SIRGT18323WQ-2MOE PFKFB1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT16323WQ-RB PFKFB1 Human Ribo-modified Inquiry
SIRGT17323WQ-BB PFKFB1 Human Backbone-modified Inquiry

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