siRNA, Anti-PGAM2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16335WQ-2OMe)

The product SIRGT16335WQ-2OMe is a type of small interfering RNA (siRNA) that targets PGAM2 gene and regulates the expression of gene. The siRNA interferes with the expression of PGAM2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000290.3
Alternative Names GSD10; PGAM-M; PGAMM
Related Diseases Glycogen Storage Disease
Purification HPLC
Target Gene
Gene ID 5224
Uniprot ID P15259
Sub Cat Target Species Modification Scale  
SIRGT17335WQ-2F PGAM2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18335WQ-2MOE PGAM2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT19335WQ-LNA PGAM2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT16335WQ-RB PGAM2 Human Ribo-modified Inquiry
SIRGT17335WQ-BB PGAM2 Human Backbone-modified Inquiry

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